Organic Electronics for Diagnostics in Physiological Media
16th November 2022
Timing : 1 pm EST
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For a list of all talks at the NanoBio seminar Series Fall'22, see here
Organic mixed (ionic and electronic) charge conductors and devices offer a new toolbox for
interfacing with biological systems. One application for which they have compelling advantages
is medical diagnostics. In this talk, I will show how we make use of the mixed conductivity of
these materials and the transistor type that relies on this type of transport to detect pathogens and
proteins with performance that exceeds the state-of-the-art. I will introduce two distinct organic
electrochemical transistors (OECT) based sensor configurations; one for Amyloid beta
aggregates and another that detects coronavirus spike proteins at the physical limit. Having
challenged these sensors with patient samples, I will discuss areas where proof-of-concept
platforms may fail and how to enhance the device operation in biological environments.
Sahika Inal
Associate Professor of Bioscience
KAUST, Saudi Arabia
Sahika Inal is an Associate Professor of Bioengineering with affiliations in Electrical
Engineering and Materials Science and Engineering at King Abdullah University of Science and
Technology (KAUST). She has a B.Sc. degree in Textile Engineering from Istanbul Technical
University (Turkey), an M.Sc. in Polymer Science, and a Ph.D. in Experimental Physics, both
from the University of Potsdam (Germany). She completed her postdoctoral training at the
Center of Microelectronics of Provence of the Ecole Nationale Supérieure des Mines de SaintÉtienne (France). Her expertise is in polymer science and bioelectronic devices, particularly in
the photophysics of conjugated polymers, characterization of polymer films and the design of
biosensors and actuators. Since 2016, Inal lab at KAUST exploits the functionalities of organic
electronic materials, investigates ionic/electronic charge transport, and designs electronic devices
that record/stimulate biological signals. Sahika is a Fellow of the Royal Society of Chemistry
and has received recognitions including ACS PMSE Young Investigator Award 2022 and Beilby
Medal and Prize 2022, and shortlisted for the Nature Research Awards for Inspiring Women in
Science in 2021. She is the author of 97+ publications and her work has been cited more than
7600 times.